Harkness Project Title:
Medicine in the 21st Century: Anticipating and Preventing Inequalities in Genetic Health Care Provision for Vulnerable Minority Populations
Mentor: Muin Khoury, M.D.
Placement: Center for Disease Control and Prevention
Biography at time of Harkness Fellowship: Nadeem Qureshi is a primary care physician and clinical associate director in primary care and honorary consultant in primary care development at the University of Nottingham. He is also director of the Clinical Genetics in Primary Care program at the NHS R&D funded Nottingham Primary Care Research Partnership and principal in general practice at The Surgery, Off Revelstoke Way, Rise Park, Nottingham. His research interests include primary care genetics and genetic health care policy. Qureshi holds a medical degree from University College London Medical School and a M.Sc. in health service research and technology assessment from the School of Health and Related Services at the University of Sheffield.
Project: Qureshi explored the intersection of preventive genetic health care and disparities among underserved minority communities. In particular, he explored how health beliefs may enhance or hinder preventive genetic care among these communities, physician competencies in providing preventive genetic services to these populations, and the impact of doctors who advise patients of familial risk. He evaluated physician competencies through interviews with primary care providers in areas with large proportions of minority populations. He also analyzed data from two surveys (Myriad; HealthStyles 2004) to explore patients’ health beliefs and community support networks.
Career Activity Since Fellowship
- Clinical Professor, Faculty of Medicine and Health Sciences, The University of Nottingham, 2013
- Clinical Reader in Primary Care, University of Nottingham and Honorary Consultant in Primary Care, NHS Derby City, 2006
Current Position: Clinical Professor, Faculty of Medicine & Health Sciences, The University of Nottingham (Updated 1/2014)
DHIMAN, P., KAI, J., HORSFALL, L., WALTERS, K. and QURESHI, N.. Availability and Quality of Coronary Heart Disease Family History in Primary Care Medical Records: Implications for Cardiovascular Risk Assessment PLoS ONE 2014; 9(1), e81998.
CHAPMAN, J., QURESHI, N. and KAI, J., 2013. Effectiveness of physical activity and dietary interventions in South Asian populations: a systematic review British Journal of General Practice 2013; 63(607), e104-e114.
WIJDENES, M., HENNEMAN, L., QURESHI, N., KOSTENSE, P.J., CORNEL, M.C. and TIMMERMANS, D.R.M. Using web-based familial risk information for diabetes prevention: a randomized controlled trial BMC Public Health 2013; 13(May), 485.
TUOMAINEN, H., CROSS-BARDELL, L., BHODAY, M., QURESHI, N. and KAI, J. Opportunities and challenges for enhancing preconception health in primary care: qualitative study with women from ethnically diverse communities BMJ Open 2013; 3(7), e002977.
QURESHI, N. and EVANS, G. Family history is key to risk classification of familial breast cancer. Guidelines in Practice 2013; 16(8), 37-45.
ALLFORD, A., QURESHI, N., BARWELL, J.G., LEWIS, C. and KAI, J.. What hinders minority ethnic access to cancer genetics services and what may help? European Journal of Human Genetics 2013.
HUSSEIN, N., QURESHI, N., WENG, S.F., KLEIJNE,N J. and KAI, J. Preconception risk assessment for thalassaemia, sickle cell disease, cystic fibrosis and Tay-Sachs disease Cochrane Database of Systematic Reviews 2012; Issue 12.
QURESHI, N., ARMSTRONG, S., DHIMAN, P., SAUKKO, P., MIDDLEMASS, J., EVANS, P.H. and KAI, J., 2012. Effect of adding systematic family history enquiry to cardiovascular disease risk sssessment in primary care: a matched-pair, cluster randomized trial Annals of Internal Medicine 2012; 156(4), 253-262
ALLFORD, A., QURESHI, N. and KAI, J.. Access to assessment of familial cancer risk by people from minority ethnic communities European Journal of Human Genetics 2012; 20(S1), 43.
CHAPMAN, J., QURESHI, N. and KAI, J.,. Effectiveness of physical activity and dietary interventions in South Asians: a systematic review British Journal of General Practice 2012.
RODGERS, S., TUOMAINEN, H., CROSS-BARDELL, L., BHODAY, M., QURESHI, N. and KAI, J. Developing a preconception health assessment intervention in primary care using the MRC guidance for developing and evaluating complex interventions.: Primary Health Care Research & Development Primary Health Care Research & Development 2012; 13(1), S31.
CROSS-BARDELL, L., BHODAY, M., TUOMAINEN, H., RODGERS, S., QURESHI, N. and KAI, J. Perceptions of risk and understanding of developing type 2 diabetes in people of South Asian origin.: Primary Health Care Research & Development Primary Health Care Research & Development 2012; 13(Supplement 1), S68
TUOMAINEN, H., BHODAY, M., CROSS-BARDELL, L., RODGERS, S., QURESHI, N. and KAI, J. Facilitating more comprehensive preconception care in general practice: what do women from higher risk communities think?: Primary Health Care Research & Development Primary Health Care Research & Development 2012; 13(Supplement 1), S71.
TUOMAINEN, H., KAI, J., BHODAY, M., CROSS-BARDELL, L., QURESHI, N. and RODGERS, S. Women's attitudes towards preconception exploration of family history of inherited conditions: a qualitative study.: Primary Health Care Research & Development Primary Health Care Research & Development 2012; 13(Supplement 1), S227.
ULPH, F., CULLINAN, T., QURESHI, N. and KAI, J. Familial influences on antenatal and newborn haemoglobinopathy screening Ethnicity & Health 2011; 16(4-5), 361-375.
WIJDENES-PIJL, M., HENNEMAN, L., CROSS-BARDELL, L., TIMMERMANS, D.R.M. and QURESHI, N.,. How does a simple enquiry compare to a detailed family history questionnaire to identify coronary heart disease or diabetic familial risk? Genetics in Medicine 2011; 13(5), 443-446.
SCULLARD, P., ABDELHAMID, A., STEEL, N. and QURESHI, N.,. Does the evidence referenced in NICE guidelines reflect a primary care population? British Journal of General Practice 2011; 61(584), 188-192.
QURESHI, N and RAEBURN, S,. Risks to offspring of consanguineous marriage: we need straight, not crooked thinking. The journal of the Royal College of Physicians of Edinburgh. 2011; 41(3), 194-195.
Valdez R, Yoon PW, Qureshi N, Green RF, Khoury MJ. “Family History in Public Health Practice: A Genomic Tool for Disease Prevention and Health Promotion.” Annu. Rev. Public Health 2010; 31: 69-87.
CLAASSEN, LIESBETH, HENNEMAN, LIDEWIJ, JANSSENS, A CECILE J W, WIJDENES-PIJL, MIRANDA, QURESHI, NADEEM, WALTER, FIONA M, YOON, PAULA W and TIMMERMANS, DANIELLE R M. Using family history information to promote healthy lifestyles and prevent diseases;a discussion of the evidence. BMC public health 2010; 10(1), 248.
FARRIMOND, H., SAUKKO, P.M., QURESHI, N. and EVANS, P.H., 2010. Making sense of being at 'high risk' of coronary heart disease within primary prevention Psychology & Health. 25(3), 289-304
QURESHI, N., ARMSTRONG, S., SAUKKO, P., SACH, T., MIDDLEMASS, J., EVANS, P.H., KAI, J., FARRIMOND, H. and HUMPHRIES, S.E. Realising the potential of the family history in risk assessment and primary prevention of coronary heart disease in primary care: ADDFAM study protocol BMC Health Services Research 2009; 9(1), 184.
RAFI, I., QURESHI, N., LUCASSEN, A., MODELL, M., ELMSLIE, F., KAI, J., KIRK, M., STAREY, N., GOFF, S., BRENNAN, P. and HODGSON, S. 'Over-the-counter' genetic testing: what does it really mean for primary care? The British journal of general practice : the journal of the Royal College of General Practitioners 2009; 59(561), 283-7.
KAI, J., ULPH, F., CULLINAN, T. and QURESHI, N. Communication of carrier status information following universal newborn screening for sickle cell disorders and cystic fibrosis: qualitative study of experience and practice Health Technology Assessment 2009; 13(57), 1-106.
QURESHI, N., CARROLL, J.C., WILSON, B., SANTAGUIDA, P., ALLANSON, J., BROUWERS, M. and RAINA, P. The current state of cancer family history collection tools in primary care: a systematic review Genetics in Medicine 2009; 11(7), 495-506.
QURESHI, N., HUMPHRIES, S.E., SEED, M., ROWLANDS, P. and MINHAS, R. Identification and management of familial hypercholesterolaemia: what does it mean to primary care? The British journal of general practice : the journal of the Royal College of General Practitioners 2009; 59(567), 773-6.
MINHAS, R, HUMPHRIES, S E, QURESHI, N, NEIL, et al. Controversies in familial hypercholesterolaemia: recommendations of the NICE Guideline Development Group for the identification and management of familial hypercholesterolaemia. Heart 2009; 95(7), 584-7; discussion 587-91.
Wilson BJ, Qureshi N, Santagulda P, et al. “Systematic Review: Family History in Risk Assessment for Common Dieseases.” Annals of Internal Medicine 2009; 151(12): 878-886.
QURESHI, N., WILSON, B., SANTAGUIDA, P., LITTLE, J., CARROLL, J., ALLANSON, J. and RAINA, P. NIH State-of-the-Science Conference: Family History and Improving Health. Evidence Report / Technology Assessment. AHRQ publication no. 09-E016 Rockville, MD: Agency for Healthcare Research and Quality.
QURESHI, N. and KAI, J. Informing patients of familial diabetes mellitus risk: how do they respond? A cross-sectional survey. BMC Health Services Research 2008; 8(1), 37.
FURLER, J., CLELAND, J., DEL MAR, C., HANRATTY, B., KADAM, U., LASSERSON, D., MCCOWAN, C., MAGIN, P., MITCHELL, C., QURESHI, N., RAIT, G., STEEL, N., VAN DRIEL, M. and WARD, A. Leaders, leadership and future primary care clinical research BMC Family Practice 2008; 9(52).
BETHEA, J, QURESHI, N, DRURY, N and GUILBERT, P. The impact of genetic outreach education and support to primary care on practitioner's confidence and competence in dealing with familial cancers. Community genetics 2008; 11(5), 289-94.
QURESHI, S.Y and QURESHI, N., 2008. Genetic profiling in primary care can enhance personalized drug therapy: reality or myth? Personalized Medicine 5(4), 311-316
PARKER, H., QURESHI, N., ULPH, F. and KAI, J. Imparting carrier status results detected by universal newborn screening for sickle cell and cystic fibrosis in England:a qualitative study of current practice and policy challenges. BMC Health Services Research 2007; 7(1), 203.
Qureshi N, Kai J. “Genomic Medicine For Underserved Minority Populations in Family Medicine,” American Family Physician 2005;72:386-387
Qureshi N, Modell B, Modell M (2004). Raising the profile of genetics in primary care Nature Genetics Review 5:783–790.
Qureshi N, Armstrong S, Modell B (2004). General Practitioners Opinions of their role in providing an initial Prenatal Genetic Counselling Service: Does the inherited condition make a difference? Family Practice.